Dean Jones

Dean P. Jones

Professor, Director of Clinical Biomarkers Laboratory, Department of Medicine, Emory University

Dr. Jones is Professor of Medicine (Division of Pulmonary, Allergy and Critical Care Medicine) with secondary appointments in Biochemistry, Pediatrics, Ophthalmology and Winship Cancer Institute at Emory University, Atlanta, GA. He is the Director of the Clinical Biomarkers Laboratory and lead the collaborative team developing high-resolution metabolomics for personalized medicine. He received a B.S. in Chemistry from the University of Illinois, Urbana, in 1971 and a Ph.D in Biochemistry from Oregon Health Sciences UniversityPortland, in 1976. He was a National Sciences Foundation Postdoctoral Fellow in Nutritional Biochemistry at Cornell University, Ithaca, and a Visiting Scientist in Molecular Toxicology at the Karolinska Institute, Stockholm, prior to moving to Emory University as Assistant Professor of Biochemistry in 1979. In 1997-98, he was a Nobel Fellow at the Karolinska Institute, Stockholm. Dr. Jones has over 200 peer-reviewed publications and over 120 invited reviews and book chapters. He has edited volumes on mitochondrial toxicity and microcompartmentation of metabolism. He received the Albert E. Levy Research Award, the most prestigious research award of Emory University. He has been a visiting professor at multiple institutions sponsored by Medical Research Council of Canada, Burroughs Wellcome Trust, and Glaxo. His research has been supported by the US National Institutes of Health, Office of Naval Research, American Heart Association, American Institute for Cancer Research as well as other sources. He has served on multiple editorial boards and grant review panels, including Chair of the Alcohol and Toxicology Study Section for NIH.

Shuzhao Li

Shuzhao Li

Assistant Professor, Associate Director of Clinical Biomarkers Laboratory, Department of Medicine, Emory University

Dr. Li was trained in bioinformatics, and he has been combining computational developments with metabolomics and systems biology. His work in human immunology applied large-scale data integration and network modeling to delineate transcriptomic programs for antibody response induced by several vaccines. These are early steps towards quantitative and systems modeling of human immunity, which is an integral part of most human diseases. His mummichog software brought genome-scale metabolic models into the field of high throughput metabolomics, and enabled pathway/network analysis for untargeted metabolomics. He strives to bring these scientific developments to personalized and precision medicine.

Young-Mi Go

Young-Mi Go

Assistant Professor, Department of Medicine, Emory University

Dr Go has extensive experience in redox biology. Her work has recently expanded to redox proteomics and high-resolution metabolomics. She is interested in applying these tools to the study of environmental toxicology and lung diseases.

Tianwei Yu

Tianwei Yu

Associate Professor, Department of Biostatistics, Rollins School of Public Health, Emory University

Dr. Yu was trained in biostatistics. His research focuses on computational methods in systems biology, high-throughput data preprocessing, genomics, and metabolomics.

Thomas Ziegler

Thomas R. Ziegler

Professor of Medicine, Division of Endocrinology, Metabolism and Lipids; Director, Emory Center for Clinical and Molecular Nutrition; Co-Program Director, Research Education, Training and Career Development Core, Atlanta Clinical and Translational Science Institute (ACTSI); Director, Emory University Hospital Research Unit, ACTSI Clinical Research Network

Dr Ziegler's research include molecular mechanisms and nutrient/growth factor/redox regulation of intestinal cell growth, repair, and function; Mechanisms and clinical effects of glutamine-supplemented nutrition support, altered macronutrient administration and high-dose vitamin D in catabolic states; and redox and metabolomic responses in malnutrition and nutritional repletion, critical illness, and with administration of specific nutrients (e.g. glutamine, sulfur amino acids, vitamin D, antioxidants) in animal and human models of disease.

Karan Uppal

Karan Uppal

Senior developer, Department Medicine, Emory University

I have a formal training in Bioinformatics with a focus on the development and application of statistical and data mining techniques for analyzing high-throughput -omics data. I developed xMSanalyzer that optimizes the performance of existing LC/MS data processing software such as apLCMS and XCMS for improved feature detection. The software allows detection of quantitatively reliable low abundance and variable chemicals and chemicals that are present in only small subset of samples. I have the expertise to integrate heterogeneous data (metabolomics and gene expressession; metabolomics and proteomics) and identify the network structure or modules of co-regulating metabolites, which would assist in characterizing the association of the unknown chemicals with respect to diseases, clinical traits, and biological pathways. I also have experience in database and Flex, PHP, ActionScript, and JavaScript based web application development.

ViLinh Tran

ViLinh Tran

Research Specialist, Department Medicine, Emory University

ViLinh was trained in high-resolution mass spectrometry at the University of Georgia, Athens. Multiple years' experience in high-resolution mass spectrometry. Responsible for the LTQ-Velos Orbitrap and Q-Exactive, and development of standard operating procedures.

Bill Liang

Bill Liang

Senior Research Specialist, Department Medicine, Emory University

Primary responsibilities for sample receipt, storage and shipping and for high-resolution metabolomics analyses of samples on the LTQ-FT in the Chemistry Department.

Dean Jones

Douglas I. Walker

Douglas Walker is a Ph.D. candidate from Tufts University and has been trained in environmental chemistry, analytical methods for quantifying environmental pollutants and mass spectrometric based chemical profiling techniques. The primary focus of his research is to integrate measures of environmental exposure, health outcomes and high performance metabolomics (HPM) in both animal models and human populations. Application of this framework using advanced biostatistic/bioinformatic techniques provides a component for sequencing the human exposome and understanding the contribution of exogenous factors in disease pathophysiology. Mr. Walker also hopes to develop HPM platforms for universal and cost-effective surveillance of anthropogenic chemicals in human populations, commercial products and ecosystems. Rapid identification and quantification of the distribution of environmental pollutants is a critical first step in protecting natural resources and mitigating exposure associated health risks.

Sophia Banton

Sophia Banton

Bioinformatics analyst, Department of Medicine, Emory University

My interdisciplinary training in both the descriptive and quantitative sciences enables me to work efficiently at the interface of biomedical and computational research. So far in my young career, I have worked on various subject areas in the Life and Biomedical Sciences, to which I have applied computational tools and techniques. These disciplines include vaccine design, systems modeling, neuroscience, genomics, and currently metabolomics. I have working knowledge of common bioinformatics tools for transcriptomics and metabolomics analysis, including R/Bioconductor, relational databases and statistical methods. My current work involves data processing and analysis for high-resolution metabolomics, quality control, data presentation and coordination of research projects.

Dean Jones

Michael Orr

Research Specialist, Department of Medicine, Emory University

Michael is our mouse expert and has extensive experience with analytical chemistry and molecular biology.

Dean Jones

Joshua Chandler

Postdoctorial fellow, Department Medicine, Emory University

Joshua Chandler received his Ph.D. in Toxicology from the University of Colorado in 2014 and his B.A. in Chemistry and Biology from Drury University in 2009. His research experience includes respiratory toxicology, infectious disease, biopharmaceutical formulation and adjuvant development. The topic of his thesis was the role of exogenous thiocyanate in infectious and inflammatory lung diseases. He has received multiple academic honors and awards including the Occupational and Public Health Speciality Section Best Graduate Student Abstract award from the Society of Toxicology.

Ken Liu

Ken Liu

Graduate student, Department of Pharmacology, Emory University

Ken is still looking for a scientific question to apply his experience in mass spectrometry and curiosity.

Andrei Todor

Andrei Todor

Bioinformatics scientist, Department Medicine, Emory University

Andrei Todor received his BS in 2004 from the Technical University of Cluj-Napoca, Romania, his MS in 2009 from Stony Brook University and his PhD in 2014 from the University of Florida, all in Computer Science. His has developed novel algorithms for probabilistic networks, demonstrated on biological data such as protein interaction networks, signaling networks and transcription regulatory networks. He is bringing his programming experience in various languages and environments as a contribution to the metabolomics efforts.